Junior starter Sean Swetnam (Greenbelt, Md./Eleanor Roosevelt/George Mason) (1-1) allowed one run in three innings of the work, but picked up the loss.
Georgetown starter Tommy Isaacs pitched five scoreless innings to move to 1-1 on the season.
Hoya Erick Fernandez went three-for-five with a home run and four runs driven in.
Wednesday's game at Delaware has been cancelled due to scheduling conflicts. The game will not be made up. The Retrievers will return to action this weekend when they open America East play against Binghamton. Saturday's doubleheader starts at 3:30, while Sunday's single game begins at 1 p.m.